How does Fildena 120 Mg work in the body?

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Fildena 120 mg is a medication primarily used to treat erectile dysfunction (ED) in men. It contains sildenafil citrate, which is a phosphodiesterase type 5 (PDE5) inhibitor. Here's how it works:

Relaxation of Blood Vessels: When a man is sexually stimulated, the body releases nitric oxide in the erectile tissue of the penis. Nitric oxide activates an enzyme called guanylate cyclase, which increases levels of cyclic guanosine monophosphate (cGMP). This leads to relaxation of the smooth muscles in the blood vessels of the penis, allowing blood to flow in and create an erection.
Inhibition of PDE5: Normally, another enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP, leading to the relaxation of the penis to cease and the erection to subside. Fildena 120 mg inhibits PDE5, allowing cGMP levels to remain elevated for a longer duration. This prolongs the vasodilation effect and helps to sustain an erection.
Erection: With increased levels of cGMP and prolonged relaxation of the smooth muscles in the penile blood vessels, more blood can flow into the penis, resulting in a firm and sustainable erection. However, sexual stimulation is still required for the medication to work effectively.
It's important to note that Fildena 120 mg should be taken as prescribed by a healthcare professional, and it may not be suitable for everyone. It's crucial to discuss any underlying health conditions and medications with a doctor before starting treatment with Fildena or any similar medication.